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Contents

Part I Therapy Response Evaluation: Science and Practice
1 Treatment Response Evaluation: Science and Practice. . . . . . . . 3
2 CT in Treatment Response Assessment in Oncology. . . . . . . . . . 11
3 MRI and Diffusion-Weighted MRI in Treatment
Response Evaluation Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
4 PET and PET-CT in Treatment Response Evaluation:
Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 27
5 Conventional Radiological Techniques and PET-CT in
Treatment Response Evaluation in Postsurgical Setting. . . . . . . 37
6 Conventional Radiological and PET-CT Assessment of
Treatment Response Evaluation in Chemotherapy Setting . . . . 49
7 Conventional Radiological Techniques and PET-CT
in Treatment Response Evaluation in Post-Radiotherapy
Setting. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 59
8 Conventional Radiological Techniques and PET-CT in
Treatment Response Evaluation in
Immunotherapy Settings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83
9 Treatment Response Evaluation of Bone
Metastases Using 18F-NaF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101
10 Reporting Post-Therapy Scans . . . . . . . . . . . . . . . . . . . . . . . . . . . 119

Part II Therapy Response Evaluation: Clinical Atlas
11 18F-FDG PET/CT in Treatment Response Evaluation
in Head and Neck Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131
12 PET/CT in Treatment Response Evaluation:
Lung Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 151
13 18F-FDG PET/CT and Non 18F-FDG-PET/CT
in Treatment Response Evaluation in Neuro-Oncology . . . . . . . 159
14 PET/CT in the Assessment of Treatment Response in
Hepatobiliary, Gall Bladder and Pancreatic Malignancies. . . . . 187
15 18F-FDG PET/CT in Treatment Response Evaluation:
Gastroesophageal Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209
16 PET-CT in Treatment Response Evaluation in Lymphoma . . . . 237
17 18F-FDG PET/CT in Treatment Response Evaluation:
Breast Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 249
18 18F-Choline, 68Ga-PSMA-11 and 18F-FDG PET/CT
in Treatment Response Evaluation: Prostate Cancer . . . . . . . . . 261
19 FDG PET/CT in Treatment Response Evaluation
of Gynecological Malignancies. . . . . . . . . . . . . . . . . . . . . . . . . . . . 297
20 [18F]FDG PET/CT in Treatment Response Evaluation:
Colorectal Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 333
21 18F-FDG PET in Treatment Response Evaluation:
Soft Tissue Sarcomas . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 357
22 18F-FDG PET-CT in Treatment Response Evaluation
in Cutaneous Malignant Melanoma . . . . . . . . . . . . . . . . . . . . . . . 377
23 18F-FDG PET-CT in Treatment Response Evaluation:
Multiple Myeloma. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 395
24 18F-FDG PET-CT and 18F-NaF in Treatment Response
Evaluation: Bone Metastases and Bone Tumours . . . . . . . . . . . . 403
25 FDG-PET/CT in Assessment of Treatment Response
in Pediatric Lymphoma . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 419
26 18F-FDG PET/CT in Treatment Response Evaluation
in Thyroid Cancer. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
27 68Ga-DOTA PET-CT in Treatment Response
Evaluation: Neuroendocrine Tumours . . . . . . . . . . . . . . . . . . . . . 453
28 18F-FDOPA PET/CT for Treatment Response Assessment . . . . . 471
29 18F-FLT/FET PET-CT in Treatment Response Evaluation . . . . 481

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