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قابل دانلود از دوشنبه, ۲۵ ارديبهشت ۱۴۰۲
فهرست مطالب: Preface ............ . . v PART III MANIPULATION OF THE EPIGENOME: PLATFORMS FOR EPIGENOME EDITING 12 Efficient Targeted DNA Methylation with dCas9-CoupledDNMT3A-DNMT3L Methyltransferase ...... . . . . 177 Pavel Bashtrykov, Nivethika Rajaram, and Albert Jeltsch 13 Regulation of Gene Expression Using dCas9-SunTag Platforms ... . 189 Sumiyo Morita, Takuro Horii, and Izuho Hatada 14 Concatenated Coiled-Coil Tag for Highly Efficient, Small Molecule-Inducible Upregulation of Endogenous Mammalian Genes ..... . . 197 Tina Lebar and Roman Jerala 15 Design, Construction, and Validation of Targeted Gene Activation with TREE System in Human Cells ....... . . 211 Atsushi Kunii, Takashi Yamamoto, and Tetsushi Sakuma PART IV MANIPULATION OF THE EPIGENOME: INDUCIBLE SYSTEM FOR EPIGENOME EDITING 16 A Split CRISPR–Cpf1 Platform for Inducible Gene Activation ... . . 229 Takahiro Otabe, Yuta Nihongaki, and Moritoshi Sato PART V MANIPULATION OF THE EPIGENOME: EPIGENETICALLY MODIFIED ANIMALS 17 Targeted DNA Methylation in Mouse Early Embryos .... . . . . 243 Taiga Yamazaki, Yu Hatano, Noritada Kobayashi, and Kazuo Yamagata 18 Generation of Epigenetic Disease Model Mice by Targeted Demethylation of the Epigenome....... . . . . 255 Takuro Horii, Sumiyo Morita, and Izuho Hatada 19 In Vivo Tissue-Specific DNA Demethylation in Mouse Liver Through a Hydrodynamic Tail Vein Injection .....269 Koshi Hashimoto and Nozomi Hanzawa 20 Targeted Manipulation of Histone Modification in Medaka Embryos .. . . 279 Hiroto S. Fukushima, Hiroyuki Takeda, and Ryohei Nakamura Index ............ . . . 295 مشخصات فایل |
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عنوان (Title): | Epigenomics_ Methods and Protocols |
نام فایل (File name): | 975-www.GeneProtocols.ir-Epigenomics_ Methods and Protocols-Humana Press (2023).pdf |
عنوان فارسی (Title in Persian): |
اپی ژنومیک - روشها و پروتکل ها
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ایجاد کننده: | Izuho Hatada, Takuro Horii |
زبان (Language): | انگلیسی English |
سال انتشار: | 2023 |
شابک ISBN: | 9781071627235 |
نوع سند (Doc. type): | کتاب |
فرمت (File extention): | |
حجم فایل (File size): | 17.1 مگابایت |
تعداد صفحات (Book length in pages): | 292 |
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