فهرست مطالب:
1 RNA and CRISPR Interferences: Past, Present, and Future Perspectives 2 Chemical Modiϐications in RNA Interference and CRISPR/ Cas Genome Editing Reagents 3 Preparation, Determination of Activity, and Biodistribution of Cholesterol-Containing Nuclease-Resistant siRNAs In Vivo 4 Multifunctional Nanodelivery Platform for Maximizing Nucleic Acids Combination Therapy 5 PAMAM Dendrimers as a Delivery System for Small Interfering RNA 6 Delivery of Functional Small RNAs via Extracellular Vesicles In Vitro and In Vivo 7 Optimized siRNA Delivery into Primary Immune Cells Using Electroporation 8 Synthesis and Evaluation of Caged siRNAs with Single cRGD Modiϐication for Photoregulating RNA Interference 9 Exploring 5′-Biotinylation of the Sense Strand to Improve siRNA Speciϐicity and Potency 10 In Vivo Delivery of Cassettes Encoding Anti-HBV Primary MicroRNAs Using an Ancestral Adeno-Associated Viral Vector 11 Generating DNA Expression Cassettes Encoding Multimeric Artiϐicial MicroRNA Precursors 12 MiR-302-Mediated Somatic Cell Reprogramming and Method for Generating Tumor-Free iPS Cells Using miR-302 13 Urinary MicroRNAs as Emerging Class of Noninvasive Biomarkers 14 Improving Dendritic Cell Cancer Vaccine Potency Using RNA Interference 15 Unleashing the Therapeutic Potential of Dendritic and T Cell Therapies Using RNA Interference 16 Harnessing the Antiviral-Type Responses Induced by Immunostimulator y siRNAs for Cancer Immunotherapy 17 Cancer Immunotherapy: Targeting Tumor-Associated Macrophages by Gene Silencing 18 Use of RNA Interference with TCR Transfer to Enhance Safety and Efϐiciency 19 CRISPR/ Cas9 Guide RNA Design Rules for Predicting Activity 20 CRISPR-Cas9 Genome Editing in Human Cell Lines with Donor Vector Made by Gibson Assembly 21 Genome Editing in Zebraϐish Using High-Fidelity Cas9 Nucleases: Choosing the Right Nuclease for the Task 22 Next Generation of Adoptive T Cell Therapy Using CRISPR/ Cas9 Technology: Universal or Boosted? 23 Engineering T Cells Using CRISPR/ Cas9 for Cancer Therapy 24 CRISPR/ Cas9-Mediated Genome Engineering of Primary Human B Cells 25 Gene Editing in B-Lymphoma Cell Lines Using CRISPR/ Cas9 Technology 26 Gene Knockout in Hematopoietic Stem and Progenitor Cells Followed by Granulocytic Differentiation 27 CRISPR/ Cas9 Genome Editing of Human-Induced Pluripotent Stem Cells Followed by Granulocytic Differentiation Index
مشخصات فایل
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عنوان (Title): |
RNA Interference and CRISPR Technologies: Technical Advances and New Therapeutic Opportunities |
نام فایل (File name): |
722-www.GeneProtocols.ir-RNA Interference and CRISPR Technologies_ Technical Advances and New Therapeutic Opportunities-Human (2020).pdf |
عنوان فارسی (Title in Persian): |
تداخل RNA و فناوریهای کریسپر CRISPR: پیشرفتهای فنی و فرصتهای درمانی جدید |
ایجاد کننده: |
Mouldy Sioud |
زبان (Language): |
انگلیسی English |
سال انتشار: |
2020 |
شابک ISBN: |
107160290X, 9781071602904 |
نوع سند (Doc. type): |
کتاب |
فرمت (File extention): |
PDF |
حجم فایل (File size): |
38.7 مگابایت |
تعداد صفحات (Book length in pages): |
686 |
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