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فهرست مطالب: Roadmap to the Development of mRNA Therapeutics: FromMolecule Design and Delivery Strategies to Manufacturing, Quality Control, and Regulatory Considerations ..... 1 Randall A. Meyer, Sara Trabulo, Julie A. Douthwaite, and Jose Luis Santos Messenger RNA for Prophylaxis ........ 17 Nicholas Jackson Messenger RNA Therapeutics: Start of a New Era in Medicine .. . . 41 Saloni Jain, Abhilash J. George, Vasu Sharma, Gagandeep Singh, and Vandana Gupta Hospital-Based RNA Therapeutics ....... . . . 73 Tulsi Ram Damase, Roman Sukhovershin, Min Zhang, Daniel L. Kiss, and John P. Cooke Medical Use of mRNA-Based Directed Gene Delivery .... . 93 A. C. Matin and Alexis Forterre SARS-COV-2 and Other mRNA Vaccines ...... . . 113 Nicholas Jackson Pulmonary Delivery of Messenger RNA (mRNA) Therapeutics for Respiratory Diseases ......... . . 139 Yingshan Qiu, Michael Yee-Tak Chow, and Jenny Ka-Wing Lam Synthetic mRNA Gene Therapies and Hepatotropic Non-viral Vectors for the Treatment of Chronic HBV Infections .... . 157 Dylan Kairuz, Prashika Singh, Tiffany Smith, Patrick Arbuthnot, Abdullah Ely, and Kristie Bloom Preparation of Synthetic mRNAs—Overview and Considerations .. 181 Siu-Hong Chan and Bijoyita Roy In Vitro-Transcribed mRNAs as a New Generation of Therapeutics in the Dawn of Twenty-First Century: Exploitation of Peptides as Carriers for Their Intracellular Delivery ...... 209 A. N. Miliotou, I. S. Pappas, I. S. Vizirianakis, and L. C. Papadopoulou Lipid Nanoparticle-Mediated Delivery of Therapeutic and Prophylactic mRNA: Immune Activation by Ionizable Cationic Lipids ........... . 237 Melike Ongun, Abhijeet Girish Lokras, Camilla Foged, and Aneesh Thakur Adjuvants, the Elephant in the Room for RNA Vaccines ...257 Sigrid D’haese, Sabine den Roover, and Joeri L. Aerts Advances in mRNA Delivery and Clinical Applications .... 277 Bo Hu, Abid Hussain, Qing Liu, Yuhua Weng, and Yuanyu Huang Lipid Nanoparticles to Harness the Therapeutic Potential of mRNA for Cancer Treatment ........ 307 Maria L. Guevara, Francesca Persano, and Stefano Persano RNA/Polymer-Based Supramolecular Approaches for mRNA Delivery ............ . . 337 Eger Boonstra, Satoshi Uchida, and Horacio Cabral Delivery Vehicles for Self-amplifying RNA ...... . 355 Nuthan Vikas Bathula, Petya Popova, and Anna Blakney Nuclear Export of mRNAs with Disease Pathogenesis and Therapeutic Implications ........ . . . 371 Shalini Guha, Priyanka Barman, Aruniti Manawa, and Sukesh R. Bhaumik Preparation of Messenger RNA-Loaded Nanomedicine Applied on Tissue Engineering and Regenerative Medicine ....397 Hsi-Kai Tsou, Cheng-Chung Chang, Tomoji Maeda, and Chin-Yu Lin Nonsequential Pre-mRNA Splicing: From Basic Understanding to Impacts on Splice-Manipulating Therapies ..... . . . 429 Kristin A. Ham, Steve D. Wilton, and May T. Aung-Htut مشخصات فایل |
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عنوان (Title): | Messenger RNA Therapeutics |
نام فایل (File name): | 1018-www.GeneProtocols.ir-Messenger RNA Therapeutics-Springer (2022).pdf |
عنوان فارسی (Title in Persian): |
درمان با آر ان ای پیامرسان
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ایجاد کننده: | Stefan Jurga, Jan Barciszewski |
زبان (Language): | انگلیسی English |
سال انتشار: | 2022 |
شابک ISBN: | 9783031084140 |
نوع سند (Doc. type): | کتاب |
فرمت (File extention): | |
حجم فایل (File size): | 11.6 مگابایت |
تعداد صفحات (Book length in pages): | 451 |
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