فهرست مطالب کتاب ضروریات بیوانفورماتیک-جلد دوم:

1 Driving Forces of Bioinformatics. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
2 Genetic Association from RFLPs to Millions of Variant Markers:
Unravelling the Genetic Complexity of Diseases . . . . . . . . . . . . . . . . . 9
3 Diagnostic Revolution Post-Human Genome Sequence Project:
High-Throughput Technologies and Bioinformatics . . . . . . . . . . . . . . 25
4 Genomic Revolution-Driven Cancer Research . . . . . . . . . . . . . . . . . . 39
5 Chromosomal Microarray in the New High-Throughput
Technological and Bioinformatic Era . . . . . . . . . . . . . . . . . . . . . . . . . . 61
Susan Mathew
6 Finding a Needle in a Haystack: Variant Effect Predictor (VEP)
to Prioritize Candidate Variants from Millions . . . . . . . . . . . . . . . . . . 85
7 Clinical Strategies for Developing Next- Generation Cancer
Precision Medicines. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 105
8 Dental Stem Cells in Regenerative Medicine: Emerging Trends
and Prospects in the Era of Bioinformatics . . . . . . . . . . . . . . . . . . . . . 119
9 Multiple Analyte Profiling (xMAP) Technology Coupled
with Functional Bioinformatics Strategies:
Potential Applications in Protein Biomarker Profiling
in Autoimmune Inflammatory Diseases . . . . . . . . . . . . . . . . . . . . . . . . 151
10 Design and Development of Small Molecules from Somatic,
Stem Cell Reprogramming, and Therapy. . . . . . . . . . . . . . . . . . . . . . . 167
11 Molecular Modeling and Drug Design Techniques
in Microbial Drug Discovery . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 185
12 Combinatorial Designing of Novel Lead Molecules Towards
the Putative Drug Targets of Extreme Drug-Resistant
Mycobacterium tuberculosis: A Future Insight
for Molecular Medicine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 233
13 Understanding the Regulatory Features of Co-regulated Genes
Using Distant Regulatory Elements (DiRE) Genomic Tool
in Health and Disease . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 283
Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 301

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