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فهرست مطالب: Preface........... . . . vContributors........... . . . . xi Contents 1 Comprehensive and High-Throughput Method for Quantitative Fingerprinting of Phenolic Compounds..... . . . . . 1 Rau´ l Gonza´lez-Domı´nguez, Ana Sayago, Marı´a Santos-Martı´n, and A´ ngeles Ferna´ndez-Recamales 2 Determination of Volatile Metabolites in Vinegar by Solid-Phase Microextraction–Gas Chromatography–Mass Spectrometry (SPME–GC–MS)......... . 13 Remedios Castro and Enrique Dura´n-Guerrero 3 Determination of Volatile Metabolites in Vinegar by Stir Bar Sorptive Extraction–Gas Chromatography–Mass Spectrometry (SBSE–GC–MS)......... . . 21 Enrique Dura´n-Guerrero and Remedios Castro 4 Discovery of Food Intake Biomarkers Using Metabolomics... 33 Leticia Lacalle-Bergeron, David Izquierdo-Sandoval, Juan V. Sancho, and Tania Portole´s 5 Metabolomic Characterization of the Antiproliferative Activity of Bioactive Compounds from Fruit By-Products Against Colon Cancer Cells........ . . . . . 45 Gerardo Alvarez-Rivera, Alberto Valde´s, and Alejandro Cifuentes 6 Untargeted Metabolomics by Liquid Chromatography–Mass Spectrometry in Biomedical Research........ . . 57 Caridad Dı´az and Carmen Gonza´lez-Olmedo 7 Untargeted Metabolomics for Disease-Specific Signatures.... . 71 Constantina Chalikiopoulou, Jose´ Carlos Gomez-Tamayo, and Theodora Katsila 8 Metabolomics Analysis of Blood, Urine, and Saliva Samples Based on Capillary Electrophoresis–Mass Spectrometry..... . . . 83 Masahiro Sugimoto and Yumi Aizawa 9 Capillary Electrophoresis–Mass Spectrometry for the Direct Analysis of Metabolites in Highly Saline Samples Using In-Capillary Preconcentration.......... . 95 Marlien van Mever and Rawi Ramautar 10 Chemical Derivatization to Enhance Capillary Electrophoresis Mass Spectrometric Analysis of Acidic Metabolites in Mammalian Cells........ . . . . . 105 Marlien van Mever and Rawi Ramautar vii viii Contents 11 Untargeted Metabolomics Based on Liquid Chromatography–Mass Spectrometry for the Analysis of Plasma and Erythrocyte Samples in Childhood Obesity........ . . . 115 A´ lvaro Gonza´lez-Domı´nguez, Marina Armeni, Otto Savolainen, Alfonso Marı´a Lechuga-Sancho, Rikard Landberg, and Rau´ l Gonza´lez-Domı´nguez 12 Characterization of the Plasmatic and Erythroid Multielemental Biodistribution in Childhood Obesity Using a High-Throughput Method for Size Fractionation of Metal Species..... . . . . 123 A´ lvaro Gonza´lez-Domı´nguez, Marı´a Milla´n-Martı´nez, Daniel Sa´nchez-Rodas, Alfonso Marı´a Lechuga-Sancho, and Rau´ l Gonza´lez-Domı´nguez 13 Analysis of Brain Metabolites Using Two Complementary Ultrahigh-Performance Liquid Chromatography–Mass Spectrometry Methods........ . . 133 Alexa M. Jauregui, Sofia E. Parellada, Emily Neag, and Sanjoy K. Bhattacharya 14 Analysis of Cholesterol from the Liver Using Gas Chromatography–Mass Spectrometry.......... . . . . 143 Meher A. Saleem, Betsy Benitez, Charles Yaros, Gabrielle Yamar, and Sanjoy K. Bhattacharya 15 Metabolomics Analysis of Aqueous Humor Based on Liquid Chromatography–Mass Spectrometry...... . 149 Karolina Pietrowska, Diana Anna Dmuchowska, Adam Kretowski, and Michal Ciborowski 16 Analyses and Localization of Serotonin and L-DOPA in Ocular Tissues by Imaging Mass Spectrometry....... . 157 Varun Krishnan, Sean Meehan, Colin Hayter, and Sanjoy K. Bhattacharya 17 Isobaric Incorporation of C13-Histidine for the Assessment of Remyelination......... . 169 Faith Christine Harvey, Anddre Osmar Valdivia, Colin Hayter, and Sanjoy K. Bhattacharya 18 Isolation and Lipidomic Screening of Human Milk Extracellular Vesicles........ . . . . 177 Victoria Ramos-Garcia, Isabel Ten-Dome´nech, Abel Albiach-Delgado, Marta Gomez-Ferrer, Pilar Sepu´ lveda, Anna Parra-Llorca, Laura Campos-Berga, Alba Moreno-Gime´nez, Guillermo Quinta´s, and Julia Kuligowski 19 Mass Spectrometry-Based Untargeted Metabolomics and Lipidomics Platforms to Analyze Cell Culture Extracts...... . . 189 Elias Iturrospe, Katyeny Manuela da Silva, Maria van de Lavoir, Rani Robeyns, Matthias Cuykx, Tamara Vanhaecke, Alexander L. N. van Nuijs, and Adrian Covaci 20 Data Processing and Analysis in Mass Spectrometry-Based Metabolomics......... . . . . 207 A´ ngela Peralbo-Molina, Pol Sola ` -Santos, Alexandre Perera-Lluna, and Eduardo Chicano-Ga´lvez Contents ix 21 Data Processing and Analysis in Liquid Chromatography–Mass Spectrometry-Based Targeted Metabolomics..... . 241 Masahiro Sugimoto, Yumi Aizawa, and Atsumi Tomita 22 Instrument-Agnostizing Methodology for Liquid Chromatography–Mass Spectrometry Systems........ . . . 257 Rosalı´a Lopez-Ruı´z, Sandra Martı´n-Torres, Ana M. Jime´nez-Carvelo, Roberto Romero-Gonza´lez, and Luis Cuadros-Rodrı´guez Index........... . . . . 271 مشخصات فایل |
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| عنوان (Title): | Mass Spectrometry for Metabolomics |
| نام فایل (File name): | 971-www.GeneProtocols.ir-Mass Spectrometry for Metabolomics-Humana Press (2023).pdf |
| عنوان فارسی (Title in Persian): |
طیف سنجی جرمی برای متابولومیک
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| ایجاد کننده: | Raúl González-Domínguez |
| زبان (Language): | انگلیسی English |
| سال انتشار: | 2023 |
| شابک ISBN: | 9781071626986 |
| نوع سند (Doc. type): | کتاب |
| فرمت (File extention): | |
| حجم فایل (File size): | 9.27 مگابایت |
| تعداد صفحات (Book length in pages): | 277 |
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