فهرست مطالب:

Preface iii
1. The CRISPR/Cas9 Genome-editing System: Principles and Applications    1
2. Recent Applications of CRISPR-Cas9 in Genome Mapping and Sequencing   23
3. Gene Editing and Genetic Disorders: Ethical and Legal Concerns    46
4. Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology    71
5. CRISPR/Cas and Gene Therapy: An Overview    85
6. CRISPR and Cancer: From Bench to Clinic   90
7. The Advances of the CRISPR/Cas9 Technology for Correcting Genetic Disorders: Using Sarcoma as a Model System    116
8. CRISPR/Cas9 Technology as a Strategy Against Viral Infections    132
9. CRISPR/Cas9-based Genome and Epigenome Editing in Neuroscience Research 158
10. Non-viral Alternatives to Delivery of CRISPR-Cas Gene Editing Components    183
11. CRISPR Medicine: Advance, Progress and Challenges    224
Subject Index 260

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