فهرست مطالب:

Contents

A Hybrid of Simple Constrained Artificial Bee Colony Algorithm

and Flux Balance Analysis for Enhancing Lactate and Succinate

in Escherichia Coli . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

Parameter Estimation of Essential Amino Acids in Arabidopsis

thaliana Using Hybrid of Bees Algorithm and Harmony Search . . . . . . 9

In Silico Modeling and Simulation Approach for Apoptosis

Caspase Pathways . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17

Molecular Dynamic Simulations Suggest that P152R Mutation

Within MeCP2 Can Lead to Higher DNA Binding Affinity

and Loss of Selective Binding to Methylated DNA . . . . . . . . . . . . . . . . . 27

Impact of Genealogical Features in Transthyretin Familial

Amyloid Polyneuropathy Age of Onset Prediction . . . . . . . . . . . . . . . . . 35

Feature Selection and Polydispersity Characterization

for QSPR Modelling: Predicting a Tensile Property. . . . . . . . . . . . . . . . 43

Methods of Creating Knowledge Graph by Linking Biological

Databases . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 52

QSAR Modelling for Drug Discovery: Predicting the Activity

of LRRK2 Inhibitors for Parkinson’s Disease Using

Cheminformatics Approaches . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 63

Improving the Use of Deep Convolutional Neural Networks

for the Prediction of Molecular Properties . . . . . . . . . . . . . . . . . . . . . . . 71

An Analysis of Symmetric Words in Human DNA:

Adjacent vs Non-adjacent Word Distances . . . . . . . . . . . . . . . . . . . . . . . 80

A Bioinformatics Protocol for Quickly Creating Large-Scale

Phylogenetic Trees . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 88

Deep Learning Analysis of Binding Behavior of Virus Displayed

Peptides to AuNPs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 97

Compression of Amino Acid Sequences . . . . . . . . . . . . . . . . . . . . . . . . . 105

NET-ASAR: A Tool for DNA Sequence Search Based

on Data Compression . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 114

Can an Integrative SNP Approach Substitute Standard

Identification in Comprehensive Case/Control Analyses? . . . . . . . . . . . . 123

Simple Pattern-only Heuristics Lead to Fast Subgraph Matching

Strategies on Very Large Networks . . . . . . . . . . . . . . . . . . . . . . . . . . . . 131

ContentsIn Silico Predictions for Fucoxanthin Production by the Diatom

Phaeodactylum Tricornutum . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 139

EvoPPI: A Web Application to Compare Protein-Protein Interactions

(PPIs) from Different Databases and Species . . . . . . . . . . . . . . . . . . . . . 149

A Review on Metabolomics Data Analysis for Cancer Applications . . . . 157

A Framework for the Automatic Combination and Evaluation

of Gene Selection Methods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 166

Parallel Cellular Automaton Tumor Growth Model . . . . . . . . . . . . . . . . 175

MOSCA: An Automated Pipeline for Integrated Metagenomics

and Metatranscriptomics Data Analysis . . . . . . . . . . . . . . . . . . . . . . . . . 183

Metabolite Integration Pipeline for the Improvement of Human

Metabolic Models . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 192

A Genetic Programming Approach Applied to Feature Selection

from Medical Data . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200

A DNA Sequence Corpus for Compression Benchmark . . . . . . . . . . . . . 208

17a-Ethinylestradiol Analysis of Endo- and Exometabolome of Ulva

lactuca (Chlorophyta) by 1H-NMR Spectroscopy

and Bioinformatics Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 216

Author Index. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225

مشخصات فایل